甲基丙二酸單酰輔酶A變位酶（英語：Methylmalonyl Coenzyme-A mutase，MCM，亦簡稱甲基丙二酰輔酶A變位酶）是一種在代謝途徑上將甲基丙二酸單酰輔酶A轉換為琥珀酰輔酶A的酶，同時需要維生素B12的幫助。
功能
甲基丙二酰輔酶A變位酶主要分布在線粒體中，催化甲基丙二酰輔酶A異構為琥珀酰輔酶A從而進入三羧酸循環。而甲基丙二酰輔酶A來源于丙酰輔酶A，后者是異亮氨酸、纈氨酸、蘇氨酸、甲硫氨酸、胸腺嘧啶、膽固醇以及奇數鏈脂肪酸分解代謝的共同中間體。
人類基因組中編碼該酶的基因縮寫為MUT。[1]
參考文獻
進一步閱讀
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